Infection rate after long-tunneled external ventricular drainage versus conventional external ventricular drainage and risk factors for intracranial infection
10.13406/j.cnki.cyxb.003659
- VernacularTitle:长程皮下隧道及常规脑室外引流术后感染率比较及颅内感染危险因素分析
- Author:
Kai WANG
1
;
Yutao WANG
;
Guangjian SHEN
;
Jianwen JI
;
Saiyu CHENG
;
Yundong ZHANG
Author Information
1. 重庆医科大学附属第三医院神经疾病中心,重庆 401120
- Keywords:
drainage;
cerebrospinal fluid shunts;
catheter-related infections;
long-tunneled external ventricular drainage;
risk factors
- From:
Journal of Chongqing Medical University
2025;50(3):409-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the difference in intracranial infection rate between long-tunneled external ventricular drainage(LTEVD)and conventional external ventricular drainage(EVD),as well as the risk factors for intracranial infection.Methods:A retro-spective analysis was performed for the clinical data of 45 patients who were admitted to Department of Neurology Center,The Third Affiliated Hospital of Chongqing Medical University,from January 2020 to December 2022 and underwent EVD,among whom 13 patients underwent LTEVD(LTEVD group)and 32 patients underwent conventional EVD(EVD group).Related data were recorded for both groups,including general information,postoperative catheter-related complications,and postoperative management,to investi-gate the effect on reducing the rate of intracranial infection.According to the presence or absence of intracranial infection after surgery,the patients were divided into the infection group with 10 patients and non-infection group with 35 patients,and related clini-cal data were analyzed to investigate the risk factors for intracranial infection.Results:The LTEVD group had a significantly lower secondary infection rate of catheterization days than the EVD group[2.40‰(1/417)vs.27.19‰(9/331),P=0.009].The duration of catheterization was 14-85 days[27.00(22.50,36.50)days]in the LTEVD group and 8-22 days[9.00(8.00,11.50)days]in the EVD group,suggesting that the LTEVD group had a significantly longer duration of catheterization than the EVD group(P=0.000).The multivariate logistic regression analysis showed that the times of cerebrospinal fluid sampling was an independent risk factor for post-operative intracranial infection in patients undergoing EVD,and the use of LTEVD was a protective factor against intracranial infection after EVD.Conclusion:Compared with conventional EVD,LTEVD can safely prolong the duration of catheterization and reduce the rate of postoperative intracranial infection in patients undergoing EVD.The use of LTEVD procedure and the reduction in the times of cerebrospinal fluid sampling can reduce the risk of postoperative in-tracranial infection.
