Progress of ferroptosis in pediatric non-Hodgkin lymphoma
10.3760/cma.j.cn115356-20241024-00159
- VernacularTitle:铁死亡在儿童非霍奇金淋巴瘤中的研究进展
- Author:
Lei CHENG
1
;
Yuqiao DIAO
;
Changping ZHAO
;
Yao LI
;
Xiuli ZHU
Author Information
1. 河北医科大学第四医院儿科,石家庄 050011
- Keywords:
Ferroptosis;
Lymphoma;
Burkitt lymphoma;
Lymphoma, large B-cell, diffuse;
Mechanism
- From:
Journal of Leukemia & Lymphoma
2025;34(7):446-448
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis was discovered and named by the laboratory of Brent Stockwell at Columbia University in 2012. Ferroptosis has become a research hotspot in the fields of life sciences, medicine and chemistry, and it now plays a significant role in the development and progression of major diseases such as neoplasms, neurodegenerative diseases, tissue and organ damage, and immune-related diseases. Non-Hodgkin lymphoma (NHL) is the most common type of lymphoma which ranks as the third most frequent malignant tumor in children in China. This paper reviews the research progress of the relationship between ferroptosis and NHL, with a particular focus on Burkitt lymphoma and diffuse large B-cell lymphoma.