Molecular biology research progress in prognosis of primary central nervous system lymphoma
10.3760/cma.j.cn115356-20240827-00131
- VernacularTitle:原发中枢神经系统淋巴瘤预后的分子生物学研究进展
- Author:
Qianru ZHAO
1
;
Zunmin ZHU
Author Information
1. 郑州大学人民医院 河南省人民医院血液内科 河南省人民医院血液病研究所，郑州 450003
- Keywords:
Lymphoma;
Central nervous system neoplasms;
Lymphoma, large B-cell, diffuse;
Diagnosis;
Treatment
- From:
Journal of Leukemia & Lymphoma
2025;34(4):245-248
- CountryChina
- Language:Chinese
-
Abstract:
Primary central nervous system lymphoma (PCNSL) is a rare hematological malignancy. PCNSL has the characteristics of strong invasiveness, high recurrence rate and poor prognosis. In recent years, there have been advances in molecular biology research related to the prognosis of PCNSL. This article mainly reviews the research progress in the immunophenotype of PCNSL and the prognosis-related gene mutations, immune checkpoints and copy number variations.
