Progress of chimeric antigen receptor T-cell therapy for malignant tumors

VernacularTitle:嵌合抗原受体T细胞治疗恶性肿瘤的研究进展
Author: Qing YANG ¹ ; Xiupin GAO
Author Information

1. 安徽医科大学临床医学院，合肥　230031
Keywords: Neoplasms; Hematologic neoplasms; Chimeric antigen receptor T-cell; Immunotherapy
From: Journal of Leukemia & Lymphoma 2025;34(1):61-64
CountryChina
Language:Chinese
Abstract: Chimeric antigen receptor T (CAR-T) cell immunotherapy is a new type of precision-targeted therapy, which can be used to modify the patient's own T cells to make them have stronger anti-tumor activity, and has achieved good results in treatment of hematologic neoplasms in recent years. Exploring the application of CAR-T cell immunotherapy in solid tumors has also been a hot research topic in recent years. The article reviews the research progress of CAR-T cell therapy for malignant tumors to provide reference for clinical application.