Predictive value of pan-immune-inflammation index for major adverse cardiovascular events within 1 year after PCI in elderly patients with coronary heart disease
10.13481/j.1671-587X.20250621
- VernacularTitle:泛免疫炎症指数对老年冠心病患者PCI术后1年内主要心血管不良事件的预测价值
- Author:
Tao SUN
1
;
Zhiyin DAI
;
Xuan LI
;
Chaopu ZHANG
;
Shu DING
;
Jianwei ZHAO
Author Information
1. 江苏大学附属医院心内科,江苏 镇江 212001
- Keywords:
Coronary heart disease;
Pan-immune inflammation index;
Major adverse cardiovascular events;
Percutaneous coronary intervention;
Elderly
- From:
Journal of Jilin University(Medicine Edition)
2025;51(6):1655-1660
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the clinical value of pan-immune inflammation index(PIV)in predicting the major adverse cardiovascular events(MACE)within 1 year after percutaneous coronary intervention(PCI)in the elderly patients with coronary heart disease,and to clarify the role of inflammatory response in postoperative recovery and prognosis of the patients with coronary heart disease.Methods:A total of 150 elderly patients with coronary heart disease who underwent PCI from July 2020 to August 2023 were selected as the research subjects;according to the occurrence of MACE within 1 year after operation,they were divided into MACE group(n=28)and non-MACE group(n=122);the baseline data and biochemical indicators of the patients were collected,and PIV was calculated;multivariate Logistic regression was used to analyze the influencing factors of MACE within 1 year after PCI in the elderly patients with coronary heart disease;receiver operating characteristic(ROC)curve was used to analyze the predictive value of PIV for MACE within 1 year after PCI in the elderly patients with coronary heart disease.Results:Compared with non-MACE group,the levels of total cholesterol(TC)and low-density lipoprotein cholesterol(LDL-C),neutrophils(NEUT),platelets(PLT)counting and PIV in the patients in MACE group were significantly increased(P<0.05);there were no significant differences in other data between two groups(P>0.05).The multivariate Logistic regression analysis results showed that the levels of TC(OR=1.571,95％CI:1.088-2.270)and LDL-C(OR=32.506,95％CI:8.880-118.994)and PIV(OR=1.014,95％CI:1.010-1.019)were the influencing factors of MACE within 1 year after PCI in the elderly patients with coronary heart disease(P<0.05).The ROC curve analysis results showed that the area under the ROC curve(AUC)of PIV for predicting MACE was 0.857(95％CI:0.762-0.951),the sensitivity was 0.821,the specificity was 0.959,the maximum Youden index was 0.780,and the best cut-off value was 778.805(P<0.01).Conclusion:PIV has important predictive value for MACE within 1 year after PCI in elderly patients with coronary heart disease.
