Analysis on influencing factors for occurrence of angina pectoris in diabetic mellitus patients and its Bayesian network risk prediction
10.13481/j.1671-587X.20250419
- VernacularTitle:糖尿病患者发生心绞痛的影响因素分析及其贝叶斯网络风险预测
- Author:
Shuang LI
1
;
Jiayu GE
;
Xianzhu CONG
;
Aimin WANG
;
Yujia KONG
;
Fuyan SHI
;
Suzhen WANG
Author Information
1. 山东第二医科大学公共卫生学院卫生统计学教研室,山东 潍坊 261053
- Keywords:
Diabetes mellitus;
Angina pectoris;
Bayesian network;
Risk prediction;
Taboo search algorithm
- From:
Journal of Jilin University(Medicine Edition)
2025;51(4):1028-1038
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the influencing factors of angina pectoris in the patients with diabetes mellitus(DM),to construct a Bayesian network model to explore the network relationships among the influencing factors,and to predict the risk of angina pectoris in the patients with DM.Methods:Based on the UK Biobank(UKB)database,the Logistic regression aralysis model was used to screen the influencing factors of angina pectoris in the patients with DM.The taboo search algorithm was used for structure learning,and the Bayesian parameter estimation method was used for parameter learning to construct the Bayesian network model.Results:A total of 22 712 DM patients were included.The influencing factors of angina pectoris in the patients with DM included 14 variables:gender,age,body mass index(BMI),triglycerides(TG),total cholesterol(TC),glycated hemoglobin(HbA1c),hypertension,maternal smoking around delivery,smoking status,alcohol consumption,regular exercise,insomnia,sleep duration,and childhood relative body size(P<0.05).A Bayesian network model was constructed with 15 nodes and 22 directed edges.Among them,age,HbA1c,hypertension,regular exercise,BMI,and sleep duration were directly associated with the occurrence of angina pectoris in the patients with DM,while gender,smoking status,alcohol consumption,TC,TG,insomnia,childhood relative body size,and maternal smoking around delivery were indirectly associated with the occurrence of angina pectoris in the patients with DM.Conclusion:Age,HbA1c,hypertension,regular exercise,BMI,and sleep duration are direct influencing factors of angina pectoris in the patients with DM.Controlling HbA1c,blood pressure,and BMI levels,engaging in regular exercise,and maintaining appropriate sleep duration are beneficial for reducing the risk of angina pectoris in the patients with DM.
