Role of biliary microbiota in the pathogenesis of bile duct stones: latest research progress
10.16139/j.1007-9610.2024.06.15
- VernacularTitle:胆管结石发病机制中胆道微生物群的作用：最新研究进展
- Author:
Xiaoning WANG
;
Xiaodong WU
;
Shuodong WU
;
Jinyan HAN
- Publication Type:Journal Article
- From:
Journal of Surgery Concepts & Practice
2024;29(6):544-548
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of bile duct stones (BDS) remains intricate and has not been fully elucidated to date. Emerging research has highlighted the biliary microbiota as a significant contributor to BDS. The diversity within the biliary microbiota correlates with stone formation, while bacterial metabolites and their self-protection mechanisms also exert pivotal roles in this process. Advanced technologies, such as high-throughput sequencing, offer fresh perspectives for in-depth exploration, and hold promise for novel strategies in the prevention and treatment of biliary tract diseases. This article comprehensively reviewed the recent advancements in research concerning the relationship and mechanisms between BDS and the biliary microbiota.
