Anti-IgLON5 encephalopathy with memory deficits: A case report and literature review
DOI: 10.19845/j.cnki.zfysjjbzz.2026.0014
- VernacularTitle:抗IgLON5脑病伴记忆力减退1例报告并文献复习
- Author:
Yuan YAN
1
;
Zhiguang WANG
1
Author Information
1. Department of Neurology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
- Publication Type:Journal Article
- Keywords:
Anti-IgLON5 encephalopathy;
Anti-IgLON5 antibody;
Special sleep disorders;
Memory deficits;
Immunotherapy
- MeSH:
Immunotherapy
- From:
Journal of Apoplexy and Nervous Diseases
2026;43(1):81-84
- CountryChina
- Language:Chinese
-
Abstract:
Anti-IgLON5 encephalopathy, also known as anti-IgLON5 antibody-associated encephalopathy, is an extremely rare autoimmune disease affecting the central nervous system. The core clinical manifestations of this disease include sleep disturbance, gait abnormalities, medulla oblongata dysfunction, and cognitive impairment, as well as the presence of anti-IgLON5 antibodies in serum and/or cerebrospinal fluid. This article reports a case of anti-IgLON5 encephalopathy with memory deficits diagnosed in our hospital, and a literature review is also conducted to enhance the understanding of this condition.