Evaluation of treatment time in total marrow irradiation using helical tomotherapy
10.13491/j.issn.1004-714X.2025.06.020
- VernacularTitle:基于螺旋断层放疗的全骨髓照射治疗时长的评估
- Author:
Fei LUO
1
;
Bo LIU
1
;
Lei ZHAO
1
;
Linan SONG
1
;
Baojin SUN
1
;
Xiaofeng MU
1
Author Information
1. Department of Radiation Oncology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
- Publication Type:OriginalArticles
- Keywords:
Total marrow irradiation;
Total marrow and lymphoid irradiation;
Helical tomotherapy;
Image-guided radiotherapy;
Treatment time
- From:
Chinese Journal of Radiological Health
2025;34(6):906-911
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution characteristics of treatment time for total marrow irradiation (TMI) or total marrow and lymphoid irradiation (TMLI) based on helical tomotherapy, establish a time parameter framework for the application of TMI/TMLI techniques, and provide a basis for optimizing clinical treatment efficiency, predicting patient tolerance, and streamlining workflow. Methods A retrospective analysis was conducted on 57 patients who received TMI/TMLI using helical tomotherapy between November 2024 and July 2025. Patients were stratified by height ( ≤ 130 cm group vs. > 130 cm group). Megavoltage computed tomography scanning time, beam-on time, and total treatment time were recorded. The relationship between height and treatment time was analyzed using Spearman correlation analysis. An independent samples t-test was used to compare treatment time between TMI and TMLI modes. Results In the ≤ 130 cm group, the mean megavoltage computed tomography scanning time, beam-on time, and total treatment time per fraction were (9.67 ± 1.47), (39.96 ± 9.08), and (49.63 ± 10.16) minutes, respectively. In the > 130 cm group, the corresponding times were (14.52 ± 1.17), (60.45 ± 11.19), and (74.97 ± 11.82) minutes, respectively. Treatment time was positively correlated with height (r = 0.756, P < 0.001). Among patients taller than 130 cm, there was no statistically significant difference in treatment time between the TMI and TMLI (P > 0.05). Conclusion Although helical tomotherapy requires a relatively long treatment time, its technical characteristics are well-suited for the extensive and complex target volumes involved in TMI/TMLI. Future technological upgrades and standardized stratification hold promise for enhancing both efficiency and precision, thereby expanding clinical applicability.
