Characterization and Application of Moisture Absorption Kinetics of Traditional Chinese Medicines Based on Double Exponential Model：A Review
10.13422/j.cnki.syfjx.20252164
- VernacularTitle:基于双指数模型的中药吸湿动力学表征及应用研究进展
- Author:
Yanting YU
1
;
Lei XIONG
2
;
Yan HE
1
;
Wei LIU
1
;
Jing YANG
3
;
Yao ZHANG
3
;
Jiali CHEN
1
;
Xiaojian LUO
1
;
Xiaoyong RAO
1
Author Information
1. Jiangxi University of Chinese Medicine，Nanchang 330004，China
2. Jiangxi Provincial Drug Certification and Evaluation Center，Nanchang 330046，China
3. National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine，Nanchang 330006，China
- Publication Type:Journal Article
- Keywords:
double exponential model;
Chinese materia medica;
moisture absorption;
kinetic models;
extracts;
solid preparations
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(5):340-346
- CountryChina
- Language:Chinese
-
Abstract:
Hygroscopicity research has long been a key focus and hot topic in Chinese materia medica（CMM）. Elucidating hygroscopic mechanisms plays a vital role in formulation design， process optimization， and storage condition selection. Hygroscopic models serve as essential tools for characterizing CMM hygroscopic mechanisms， with various types available. The double exponential model is a kinetic mathematical model constructed based on the law of conservation of energy and Fick's first law of diffusion， tailored to the physical properties of CMM extracts. In recent years， this model has been extensively applied to simulate the dynamic moisture absorption behavior of CMM extracts and solid dosage forms under varying humidity conditions. It has revealed the correlation between moisture absorption kinetic parameters and material properties， offering a new perspective for characterizing the moisture uptake behavior of CMM. This paper systematically reviews the application progress of this model in the field of CMM， analyzes its advantages， disadvantages， and challenges in this domain， and explores its potential application trends in other fields. It aims to provide references for elucidating the moisture absorption mechanisms of CMM and researching moisture-proofing technologies， while also offering insights for its broader application in food and polymer materials.
