Miller-Fisher syndrome： A case report
10.19845/j.cnki.zfysjjbzz.2025.0206
- VernacularTitle:Miller-Fisher综合征1例报告
- Author:
Yi ZHANG
1
;
Xuemei LI
1
;
Jie LI
1
Author Information
1. Department of Neurology，The Affiliated Hospital of Shandong Second Medical University， Weifang 261000， China
- Publication Type:Journal Article
- Keywords:
Miller-Fisher syndrome;
Ophthalmoplegia;
Aigamoide α injection
- MeSH:
Ophthalmoplegia
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(12):1141-1144
- CountryChina
- Language:Chinese
-
Abstract:
Miller-Fisher syndrome （MFS） is a rare neurological disorder and a variant of Guillain-Barré syndrome， with the main manifestations of ophthalmoplegia， ataxia， and absent tendon reflexes， and there are rare case reports of complete eyeball fixation. This article reports a case of MFS with complete eyeball fixation， and the patient had no response to conventional treatment and was improved after treatment with aigamoide α injection. Aigamoide α injection binds to Fc receptors in the body and accelerates the degradation of pathogenic immunoglobulin G （IgG） antibodies in lysosomes， thereby blocking the IgG cycle， and therefore， it is expected to become a potential therapy for GBS.
