认知行为疗法对功能性发作有效性及安全性的评价研究
10.19845/j.cnki.zfysjjbzz.2025.0203
- VernacularTitle:Efficacy and safety of cognitive behavioral therapy in treatment of functional seizures
- Author:
Jiyuan ZHONG
1
;
Yangmei CHEN
2
Author Information
1. 重庆医科大学附属第一医院，重庆 400016
2. 重庆医科大学附属第二医院，重庆 400016
- Publication Type:Journal Article
- Keywords:
Cognitive behavioral therapy;
Treatment;
Functional seizure;
Meta-analysis
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(12):1126-1130
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of cognitive behavioral therapy （CBT） in the treatment of functional seizures （FS）. Methods Databases including PubMed （MEDLINE）， EMBASE， and the Cochrane Library were searched for randomized controlled trials （RCTs） on CBT in the treatment of FS published from January 2001 to October 2024. Jadad score was used to assess the quality of studies， and stata16 software was used to perform the meta-analysis. Results Four RCTs involving 463 patients were included in this meta-analysis. The analysis showed that CBT could reduce the frequency of FS by ≥50% （OR=0.57， 95%CI 0.36~0.78， P<0.001）， achieve complete remission of seizures （OR=1.83， 95% CI 1.09~3.05， P=0.021）， improve the degree of satisfaction among patients （MD=1.12， 95%CI -2.28~0.04， P=0.050）， and enhance the quality of life and work （OR=0.50， 95%CI 0.47~0.52， P<0.001）. Conclusions While CBT can help achieve full remission in FS， more research is needed to confirm its effectiveness in reducing episodes by over 50% and improving patients’ quality of life， family functioning， social adaptability， and psychological well-being.
- Full text:202601230826456376认知行为疗法对功能性发作有效性及安全性的评价研究.pdf
