Research progress of mitochondrial quality control and neurodegenerative diseases
10.19405/j.cnki.issn1000-1492.2025.02.025
- VernacularTitle:线粒体质量控制与神经退行性疾病的研究进展
- Author:
Lu Guan
1
;
Rili Ge
2
;
Shuang Ma
2
Author Information
1. Graduate School of Qinghai University, Xining 810001; Graduate Management Department of Afiliated Hospital of Qinghai University, Xining 810001
2. Graduate School of Qinghai University, Xining 810001; Plateau Medicine Research Center , Medical College of Qinghai University, Xining 810001; Key Laboratory of Qinghai Applied Basic Sciences , Xining 810001
- Publication Type:Journal Article
- Keywords:
mitochondrion;
quality control;
neurodegenerative diseases;
alzheimer / s disease;
parkinson / s dis- ease;
huntington /s disease;
amyotrophic lateral sclerosis
- From:
Acta Universitatis Medicinalis Anhui
2025;60(2):357-365
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Neurodegenerative diseases include Alzheimer′s disease, Parkinson′s disease, Huntington′s disease, amyotrophic lateral sclerosis, and other disease. There are many causes of neurodegenerative diseases, and the pathogenesis is not entirely clear. Currently, most scholars believe that the occurrence of diseases is closely related to mitochondria. Mitochondrial quality control includes the production, fusion, division, and clearance of mitochondria. Abnormal mitochondrial quality control affects the function of neurons and nerve fibers, leading to the occurrence of neurodegenerative diseases. The author elaborates on the relationship between mitochondria and the pathogenesis of neurodegenerative diseases, providing a basis for the treatment of neurodegenerative diseases.
- Full text:2026012216404900952线粒体质量控制与神经退行性疾病的研究进展_关璐.pdf
