Research advances in exosomal proteins in the diagnosis and treatment of cerebral small vessel disease and related cognitive impairment
10.19845/j.cnki.zfysjjbzz.2025.0199
- VernacularTitle:外泌体蛋白在脑小血管病及相关认知障碍诊疗中的研究进展
- Author:
Mengxi HAN
1
;
Dan YANG
1
;
Yun XU
1
Author Information
1. Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University，Nanjing 210008，China
- Publication Type:Journal Article
- Keywords:
Cerebral small vessel disease;
Cognitive impairment;
Exosomal proteins;
Biomarkers;
Therapeutic targets
- MeSH:
Biomarkers
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(12):1095-1099
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease （CSVD） is an important etiology of vascular cognitive impairment and stroke， and there are still many challenges in its early diagnosis and pathological mechanisms. As a type of extracellular vesicles that exist stably in body fluids and can cross the blood-brain barrier， exosomes have attracted wide attention in recent years. Studies have shown that various exosomal proteins have a potential value in the diagnosis and treatment of CSVD and related cognitive impairment， providing new research directions for the noninvasive management of these diseases. This article systematically reviews the latest advances in exosomal proteins for the diagnosis and treatment of CSVD and related cognitive impairment， in order to provide new perspectives for the application of exosomal proteins in the precise treatment of CSVD.
- Full text:2026012216081139397外泌体蛋白在脑小血管病及相关认知障碍诊疗中的研究进展.pdf
