Research advances in obstructive sleep apnea-hypopnea syndrome comorbid with cerebral small vessel disease
10.19845/j.cnki.zfysjjbzz.2025.0198
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征共病脑小血管病的研究进展
- Author:
Ruozhu XIONG
1
;
Yun XU
1
Author Information
1. Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University，Nanjing 210008，China
- Publication Type:Journal Article
- Keywords:
Obstructive sleep apnea‐hypopnea syndrome;
Cerebral small vessel disease;
Neuroimaging biomarkers
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(12):1089-1094
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea-hypopnea syndrome（OSAHS） is a prevalent sleep-related breathing disorder characterized by recurrent pharyngeal collapse during sleep，and it is recognized as an important risk factor for cardiovascular and cerebrovascular events. Cerebral small vessel disease（CSVD） refers to a series of clinical， imaging， and pathological syndromes that arise from pathological alterations in the small arteries， arterioles， capillaries， venules， and small veins within the brain. There is a close association between OSAHS and CSVD，and OSAHS is significantly associated with various neuroimaging biomarkers for CSVD.This article reviews the current status of research on the association between the imaging features of OSAHS and CSVD and related mechanisms， in order to provide a reference for future research.
- Full text:2026012216013518377阻塞性睡眠呼吸暂停低通气综合征共病脑小血管病的研究进展.pdf
