Research progress on the damage to the reproductive system and the mechanisms induced by bisphenol S
- VernacularTitle:Research progress on the damage to the reproductive system and the mechanisms induced by bisphenol S
- Author:
Lianman Lei
1
;
Shu Shu
1
;
Chen Chen
1
;
Chen Zhang
2
;
Zhang Hao
1
Author Information
- Publication Type:Journal Article
- Keywords: Bisphenol S; testis; ovary; reproductive toxicity; oxidative stress; gonadotropins
- From: Acta Universitatis Medicinalis Anhui 2025;60(1):180-185
- CountryChina
- Language:Chinese
- Abstract: Abstract : Bisphenol S is commonly utilized in the industry as a substitute for bisphenol A．However，numerous studies have indicated that bisphenol S also exhibits a wide range of toxicity．Bisphenol S has been found to cause adverse effects on the nervous system，endocrine system，reproductive system，etc．，with more extensive studies on the reproductive system．Specifically，bisphenol S exposure causes a decrease in sperm count，decreases motility and increases malformations，and decreases testosterone levels in males; on the other hand，bisphenol S exposure causes a significant reduction in ovarian volume and relative weight，affectes oocyte quality，decreases gonadotro- pins follicle-stimulating hormone，and luteinizing hormone in females．The mechanisms by which bisphenol S af- fects the body are complex and varied，involving oxidative stress，cell death，and epigenetic modifications．Nota- bly，the reproductive toxicity of bisphenol S varies in different studies．As a result，this paper reviews the reproduc- tive toxicity of bisphenol S and its underlying mechanisms．
- Full text:2026012117313794093双酚S暴露致生殖系统损伤及其机制的研究进展_雷连曼.pdf
