Criteria for pancreas donor selection in islet transplantation and the experience of Changzheng hospital
10.12464/j.issn.1674-7445.2025228
- VernacularTitle:用于胰岛移植的胰腺供者选择标准及长征经验
- Author:
Hanxiang ZHONG
1
;
Junfeng DONG
1
;
Wenyuan GUO
1
;
Shengxian LI
1
;
Hao YIN
1
;
Yuanyu ZHAO
1
;
Junsong JI
1
Author Information
1. Department of Liver Transplantation, the Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital), Shanghai 200003, China.
- Publication Type:ReviewArticle
- Keywords:
Islet transplantation;
Diabetes mellitus;
Donor selection;
Donor evaluation;
Age;
Body mass index;
Cold ischemia time;
Warm ischemia time
- From:
Organ Transplantation
2026;17(1):164-169
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus, characterized by glucose metabolism disorders and marked by insulin deficiency or insulin resistance, has seen a continuous rise in prevalence. In recent years, islet transplantation has matured as a therapeutic approach for diabetes, becoming an important method for glycemic control and the reduction of diabetes-related complications. Donor selection directly influences transplant outcomes, and various research institutions worldwide have proposed multiple scoring systems to optimize donor assessment, such as the University of Alberta scoring system and the North American Islet Donor Score. This article explores the impact of key factors such as donor age, body mass index and ischemia time on islet transplantation. Combining practical experience in pancreatic donor selection from Shanghai Changzheng Hospital, it proposes screening criteria for pancreatic donors suitable for China, aiming to provide new evidence for improving the success rate of islet transplantation.
