Current Status of Traditional Chinese Medicine Diagnosis and Treatment of Inflammatory Bowel Disease and the Research on Mechanism
10.13288/j.11-2166/r.2026.01.016
- VernacularTitle:炎症性肠病中医药诊疗及机制研究现状
- Author:
Junxiang LI
1
;
Hong SHEN
2
;
Tangyou MAO
1
;
Lei ZHU
2
;
Jiaqi ZHANG
3
;
Zhibin WANG
1
;
Xudong TANG
3
Author Information
1. Dongfang Hospital，Beijing University of Chinese Medicine，Beijing，100078
2. Jiangsu Province Hospital of Chinese Medicine
3. Institute of Gastroenterology，Xiyuan Hospital，China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
inflammatory bowel disease;
ulcerative colitis;
Crohn's disease;
traditional Chinese medicine;
literature review
- From:
Journal of Traditional Chinese Medicine
2026;67(1):103-110
- CountryChina
- Language:Chinese
-
Abstract:
In recent years， traditional Chinese medicine （TCM） has achieved significant progress in the treatment of inflammatory bowel disease （IBD）. A comprehensive literature search was conducted covering the period from January 1， 2010， to December 30， 2024， across Chinese databases including China National Knowledge Infrastructure （CNKI）， Wanfang Data， VIP China Science and Technology Journal Database， and the Chinese Biomedical Literature Service System， as well as international databases such as PubMed， Web of Science， and Embase. The clinical applications and mechanistic studies of TCM in IBD were systematically reviewed. The current status of TCM research on the etiology and pathogenesis of IBD， innovative clinical practices， and multimodal therapeutic approaches， including Chinese herbal formulas， single herbs or active compounds， acupuncture， herbal retention enema， and acupoint application， were summarized， together with their synergistic effects when combined with western medical treatments. The development and application of Chinese patent medicines for IBD are undergoing a profound transition from efficacy validation to mechanistic exploration. Mechanistic studies on the effects of TCM in IBD mainly focus on regulating gut microbiota homeostasis， repairing the intestinal mucosal barrier， and modulating intestinal immune balance. Furthermore， future research directions for TCM-based IBD management are proposed， including the establishment of TCM diagnostic and treatment models， expanding integrated applications of external and internal TCM therapies， innovating personalized treatment strategies， and advancing drug development. These efforts aim to provide insights for the standardized and precision-oriented development of TCM in the diagnosis and treatment of IBD.
