Pathogenesis and Prevention Strategies of Hypercoagulable State in Malignant Tumors Based on the Theory of "Sweet-Flavored Medicinals Retaining and Restoring Body Fluid"
10.13288/j.11-2166/r.2026.01.005
- VernacularTitle:基于“甘守津还”探讨恶性肿瘤高凝状态的病机与防治
- Author:
Yong WANG
1
;
Zixuan CHENG
2
;
Weiyang KONG
1
;
Yuwei SUN
1
;
Yunxuan SHI
1
;
Ruyu QIN
1
;
Zhaidong LIU
1
Author Information
1. First Clinical Medical College，Shandong University of Traditional Chinese Medicine，Jinan，250355
2. The Affiliated Hospital of Shandong University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
malignant tumors;
hypercoagulable state;
sweet-flavored medicinals retaining and restoring body fluid;
YE Gui;
body fluids;
sweet-flavored medicinals
- From:
Journal of Traditional Chinese Medicine
2026;67(1):26-30
- CountryChina
- Language:Chinese
-
Abstract:
Based on the theory of "sweet-flavored medicinals retaining and restoring body fluid"， this paper proposed that the core pathogenesis of hypercoagulable state in malignant tumors is qi deficiency and fluid consumption， blood stasis and vessels stagnation， which evolves dynamically according to the pattern "qi deficiency → fluid consumption → blood stasis". Accordingly， a staged treatment system is established with the general principle of "fortifying the middle jiao， restoring fluid and activating blood circulation". In the initial stage， invigorating the spleen and boosting qi to generate body fluid， targeting the onset of middle jiao deficiency and body fluid consumption； in the middle stage， nourishing yin and unblocking collaterals to facilitate body fluid circulation， addressing the disorder of body fluid transportation and collateral injury caused by internal dryness； in the late stage， consolidating yin and resolving blood stasis to retain body fluid， resolving yin impairment， fluid exhaustion， and binding of stasis and toxin. By regulating body fluid metabolism to improve the hypercoagulable state， this system is intended to provide insights for the prevention and treatment of hypercoagulable state in malignant tumors with traditional Chinese medicine.
