Stress is a pervasive occupational hazard among healthcare workers, particularly in tertiary government hospitals with heavy workloads, limited resources, and emotionally demanding care. Chronic stress contributes to burnout, reduced job performance, and poorer patient outcomes, posing significant workforce and public health concerns. Despite post-pandemic recovery initiatives, evidence remains limited on how healthcare workers experience and manage stress in routine, non-crisis settings in Philippine tertiary hospitals. This study aimed to examine the relationship between perceived stress, clinicodemographic and lifestyle factors among employees of a tertiary government hospital.

An analytical cross-sectional study was conducted among 173 stratified randomly selected employees of Luis Hora Memorial Regional Hospital (LHMRH), Mountain Province. A validated self-administered electronic questionnaire assessed clinicodemographic characteristics, lifestyle behaviors, and the 10-item Perceived Stress Scale. Anthropometric measures, including body mass index and waist-to-hip ratio, supplemented self-reported data. Descriptive statistics summarized participant characteristics, and linear regression identified factors associated with perceived stress.

Most employees demonstrated suboptimal adherence to Lifestyle Medicine pillars, particularly nutrition (0.6% met recommendations), physical activity (61.8% low), and sleep quality (83.3% fair/poor). The overall perceived stress level was moderate (mean = 18.19). Linear regression revealed that bronchial asthma (p = 0.003), poor sleep quality (p < 0.001), and alcohol dependence (p = 0.023) were significantly associated with higher stress, while nutrition, physical activity, and social support were not.

Healthcare workers at LHMRH experience moderate stress primarily linked to poor sleep, alcohol dependence, and bronchial asthma. Targeted wellness programs promoting sleep hygiene, responsible alcohol use, and chronic disease management are recommended to strengthen workforce resilience and align with the Mental Health Act and Civil Service Commission directives.