Headaches are among the top reasons for consultation in primary care clinics and can be classified either as primary or secondary. Primary headaches are unrelated to any medical condition and usually benign in nature. Secondary headaches are caused by an underlying pathology or condition. The mnemonic “HEADACHES” may be used to remember the red flags and it includes: Headache of sudden onset, Elderly onset, Altered mental status or neurologic deficits, Different or new pattern, Associated systemic symptoms, Cancer or immunocompromised state, Headache with exertion or position change, Eye findings and Secondary risk factors. Patients presenting with red flags are suggested to have underlying causes or secondary headaches and presence of which warrants diagnostic investigation or referral to specialists. Diagnostic imaging is not routinely recommended for patients with headache unless presenting with red flags or with suspected underlying pathology.