Research progress in chemical constituents and pharmacological activities of Inonotus obliquus
10.11665/j.issn.1000-5048.2024051101
- VernacularTitle:桦褐孔菌化学成分及药理活性研究进展
- Author:
Jiamin CUI
1
;
Hairan FAN
;
Haimin KUAI
;
Xiaolong HU
;
Hao WANG
Author Information
1. 中国药科大学中药学院, 南京 210009
- Publication Type:Journal Article 期刊文章
- Keywords:
Inonotus obliquus;
chemical constituents;
lanostane-type triterpenoids;
pharmacological activity
- From:
Journal of China Pharmaceutical University
2025;56(4):515-523
- CountryChina
- Language:Chinese
-
Abstract:
As a medicinal and edible fungus, Inonotus obliquus has a long history of folk application in Russia, Japan, and Northeast China. It is rich in terpenoids, steroids, polysaccharides, phenols, alkaloids, etc, and exhibits pharmacological activities including anti-tumor, hypoglycemic, anti-inflammatory, antioxidant, and lipid-lowering effects. Among these, lanostane-type tetracyclic triterpenes represent its characteristic constituents. This review systematically summarizes the research progress on the chemical components isolated and identified from I. obliquus and their pharmacological activities in recent years. The structures of terpenoids, steroids, and phenolic compounds are compiled and illustrated, with a particular focus on the skeletal types and structural characteristics of lanostane-type tetracyclic triterpenes. This work aims to provide some reference for the further investigation and comprehensive development and utilization of I. obliquus.
