Impact of donor characteristics on red blood cell quality and transfusion outcomes
10.13303/j.cjbt.issn.1004-549x.2025.12.021
- VernacularTitle:献血者特征对其红细胞质量和受血者输血结局的影响
- Author:
Peng LI
1
;
Kaiqiang LIU
2
;
Mingming QIAO
3
;
Xia YANG
4
;
Shenglan WANG
4
;
Xia HUANG
5
Author Information
1. Yichang Red Cross Central Blood Station, Yichang 443005, China
2. Wenshan Zhuang and Miao Autonomous Prefecture Central Blood Station, Wenshan 663099, China
3. Shandong Blood Center, Jinan 250013, China
4. Liangshan Yi Autonomous Prefecture Central Blood Station, Xichang 6150995, China
5. Chongqing Blood Center, Chongqing 402160, China
- Publication Type:Journal Article
- Keywords:
blood transfusion;
blood quality;
donor variability;
transfusion outcomes
- From:
Chinese Journal of Blood Transfusion
2025;38(12):1786-1793
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To systematically analyzes the impact of blood donor characteristics on red blood cell (RBC) quality and transfusion outcomes, and to provide a scientific basis for optimizing donor selection criteria and developing personalized transfusion strategies. Methods: A literature search was conducted across electronic databases including CNKI, VIP, Wanfang Data, PubMed, and Embase using combinations of keywords such as "donor characteristics", "blood storage lesion", "blood quality", and "transfusion outcomes" for summary and analysis. Results: Factors associated with the blood donor characteristics including demographic characteristics (sex, age, body mass index), lifestyle habits (smoking, alcohol consumption, exercise), and dietary or pharmacological exposures significantly influence blood storage stability and transfusion efficacy by modulating erythrocyte metabolism, oxidative stress levels, and immune properties. Conclusion: The complexity and diversity of the blood donor characteristics are associated with blood quality and transfusion outcomes. Future efforts should focus on refining donor selection criteria and establishing personalized transfusion strategies to enhance blood product quality and improve patient outcomes.
