Lapse rate and influencing factors of voluntary blood donation in China: a meta-analysis
10.13303/j.cjbt.issn.1004-549x.2025.12.020
- VernacularTitle:中国无偿献血流失率及其影响因素Meta分析
- Author:
Shuyun SUN
1
;
Chenjia HUANG
2
;
Ye HE
2
Author Information
1. Shanghai Blood Center, Shanghai 200051, China; School of Social and Public Administration, East China University of Science and Technology, Shanghai 200237, China
2. Shanghai Blood Center, Shanghai 200051, China
- Publication Type:Journal Article
- Keywords:
blood donors;
lapse rate;
meta-analysis
- From:
Chinese Journal of Blood Transfusion
2025;38(12):1779-1785
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To systematically evaluate the lapse rate of voluntary blood donation in China, and to provide theoretical reference for blood centers to develop donor retention strategies. Methods: Cross-sectional studies on the lapse rate of voluntary blood donation and its influencing factors, published between January 2015 and May 2024, were retrieved from the CNKI, Wanfang Data, VIP, PubMed, Web of Science and The Cochrane Library databases. Two reviewers independently screened the literature and extracted data, and Review Manager 5.4 software was used for meta-analysis. Results: A total of 14 literature involving 428 343 lapsed blood donors were included. Meta-analysis showed that the overall lapse rate of blood donation in China was 47.0% [95% CI(33.0, 61.0)]; and age among 18 to 25[OR=1.40, 95% CI(1.02, 1.92)], no previous donation history [OR=4.54, 95% CI(2.13, 9.67)], relocation from the city of last donation [OR=2.89, 95% CI(1.13, 7.37)], low satisfaction [OR=1.80, 95% CI(1.42, 2.28)], adverse reactions [OR=1.92, 95% CI(1.07, 3.45)], and negative public opinion [OR=2.72, 95% CI(1.23, 6.02)] were the influential factors for blood donors. The sub group analysis results showed that the lapse rate of blood donation in China during different research period was 44.0%[95% CI (26.7, 62.4)] from 2017 to 2019 and 50.0%[95% CI(37.2, 63.1)] from 2020 to 2023; and the lapse rate of blood donors was 42.0%[95% CI(31.8, 52.8)] among platelet donors and 64.0%[95% CI(52.2, 83.2)] among whole blood donors. Sensitivity analysis suggests that the research results are stable, and the funnel diagram combined with Egger test and Begg' test shows that there is no publication bias. Conclusion: The lapse rate of blood donation remains relatively high in China. Blood centers should take measures such as strengthening guidance for first-time blood donors, promoting refined services, implementing predictive interventions, and improving to monitor the social media to enhance blood donor's willingness for donating repeatedly and reduce the lapse rate of blood donors.