The seroepidemiological characteristics of Toxoplasma gondii infection among blood donors in Jiangxi Province
10.13303/j.cjbt.issn.1004-549x.2025.12.004
- VernacularTitle:江西省献血者人群弓形虫血清流行病学特征分析
- Author:
Yanglin ZHUANG
1
;
Xinyu GUO
1
;
Fang WANG
1
;
Dan CHEN
2
Author Information
1. Jiangxi Blood Center, Nanchang 330077, China
2. Jiangxi Provincial Institute of Occupational Disease Prevention and Control, Nanchang 330000, China
- Publication Type:Journal Article
- Keywords:
blood donors;
Toxoplasma gondiiinfection;
residual transfusion risk
- From:
Chinese Journal of Blood Transfusion
2025;38(12):1673-1677
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the current status of Toxoplasma gondii (T. gondii) infection among blood donors in Jiangxi Province, thereby providing scientific evidence for ensuring blood transfusion safety. Methods: Serum samples from 1 529 blood donors were tested for T. gondii IgG and IgM antibodies using enzyme-linked immunosorbent assay (ELISA). Positive samples were further analyzed by B1 gene PCR testing and Giemsa staining microscopy. Risk factor data were collected via telephone follow-up. Infection rate differences were analyzed using χ
tests. Results: The overall T. gondii infection rate among blood donors was 3.92% (60/1 529), with IgG positivity being predominant (3.86%) and IgM positivity at 0.20%. All antibody-positive samples tested negative for T. gondii DNA. Blood group AB donors had the highest infection rate (7.00%), whereas group O donors had the lowest rate (2.47%), with a statistically significant difference (χ
=8.27, P<0.05). The infection rate in the 46-55 age group was higher than that in the 18-25 age group, χ
=4 237.75, P<0.05. No significant differences were observed across subgroups stratified by sex, occupation, or education level. Multivariate analysis identified cat/dog ownership (χ
=28.23, P<0.05), and frequent consumption of cold dishes (χ
=4.09, P<0.05) as key risk factors. Conclusion: In Jiangxi province, T. gondii infection among blood donors is predominantly characterized by past infection, with higher infection rates observed in blood type AB donors and those aged 46-55. The main risk factors include contact with cats/dogs as pets and frequent consumption of cold dishes. It is recommended to disseminate health knowledge on toxoplasmosis prevention in communities and schools to reduce the transfusion transmission risk.
