Clinical efficacy analysis of endoscopic resection of large diameter duodenal papilla tumors
10.12025/j.issn.1008-6358.2025.20250349
- VernacularTitle:内镜下切除大直径十二指肠乳头肿瘤的临床疗效分析
- Author:
Tianyu ZHANG
1
;
Zhanghan CHEN
1
;
Dongli HE
2
;
Yunshi ZHONG
1
;
Yan WANG
3
Author Information
1. Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
2. Endoscopy Center, Zhongshan Hospital (Xuhui Hospital), Fudan University, Shanghai 200031, China.
3. Department of Gastroenterology, Rongcheng Hospital of Traditional Chinese Medicine, Weihai 264300, Shandong, China.
- Publication Type:Monographicreport:Endoscopicdiagnosisandtreatmentofdigestivesystemdiseases
- Keywords:
duodenal papilla tumor;
endoscopic resection;
large diameter;
efficacy evaluation
- From:
Chinese Journal of Clinical Medicine
2025;32(5):755-760
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility and clinical value of endoscopic resection of duodenal papilla tumors with a maximum diameter greater than 3 cm. Methods A retrospective analysis was conducted on the clinical data of all 12 patients who underwent endoscopic resection of duodenal papilla tumors at the Endoscopy Center of Zhongshan Hospital (Xuhui Hospital), Fudan University and Rongcheng Hospital of Traditional Chinese Medicine from September 2017 to May 2023. The size of the tumors all exceeded 3 cm. Results All 12 patients successfully completed the operation, with a complete resection rate of 91.7% (11/12) and an en-bloc resection rate of 91.7% (11/12). One patient experienced delayed bleeding due to unclosed wound during operation and received endoscopic hemostasis; 11 cases underwent partial wound closure operation with pancreatic and biliary stent placement, without perforation or postoperative stenosis. Among them, 2 cases (18.2%) experienced delayed bleeding and received endoscopic hemostasis treatment. After operation, 1 case (8.3%) experienced nausea, vomiting, upper abdominal discomfort, and elevated blood amylase levels, who was later treated conservatively. During the mean follow-up period of 30.5 (1.0-69.0) months, 1 patient experienced recurrence and underwent surgical resection. Conclusions Endoscopic resection of duodenal papilla tumors can treat large diameter duodenal papilla tumors exceeding 3 cm, but postoperative complications may occur and require special attention. Postoperative placement of pancreatic and biliary stents and wound closure may reduce the incidence of complications.
