Influence of blood pressure level on optical coherence tomography angiography parameters in patients with essential hypertension
10.12025/j.issn.1008-6358.2025.20251092
- VernacularTitle:原发性高血压患者血压水平对光学相干断层扫描血管成像技术参数的影响
- Author:
Jinbao MA
1
;
Kai CAO
2
;
Guohong WANG
1
;
Mingzhao QIN
1
;
Xue JIANG
3
;
Caixia GUO
3
;
Yu HE
1
;
Yongpeng ZHANG
4
;
Qi LIU
1
Author Information
1. Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
2. Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
3. Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
4. Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
- Publication Type:Originalarticle
- Keywords:
essential hypertension;
optical coherence tomography angiography;
optic disc;
macula;
vessel density
- From:
Chinese Journal of Clinical Medicine
2025;32(6):967-972
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the changes in optical coherence tomography angiography (OCTA) parameters in patients with essential hypertension，and to explore the effect of blood pressure on OCTA parameters. Methods A total of 164 patients with essential hypertension were selected and divided into controlled blood pressure group (n=92) and uncontrolled blood pressure group (n=72). OCTA examination was performed on the optic disc and macula of all patients, and the right eyes were selected for analysis. Results There were no significant differences in retinal nerve fiber layer (RNFL) thickness, radial peripapillary capillary (RPC) total vascular density, RPC total small vessel density, perifovea superficial capillary plexus (SCP) vascular density, and perifovea deep capillary plexus (DCP) vascular density between the two groups of patients. There were no significant differences in foveal avascular zone (FAZ) area, FAZ diameter, and fovea retinal thickness between the two groups of patients. The density of the parafovea SCP, parafovea DCP, and fractal dimension (FD) in the uncontrolled blood pressure group were significantly lower than those in the controlled blood pressure group (P＜0.05). Multiple linear regression analysis showed that elevation of blood pressure was a independently related factor of reduced parafovea DCP density (P＝0.026), while there was no correlation between the uncontrolled blood pressure and parafovea SCP density and FD level. Conclusions The blood pressure level is correlated with the parafovea DCP density, while has no correlation with other OCTA parameters in hypertension patients.
