Principle and characteristics of the mapping/selective renal denervation system and its research progress in hypertension treatment
10.12025/j.issn.1008-6358.2025.20250548
- VernacularTitle:标测/选择性去肾神经术系统的原理特征及在高血压治疗领域研究进展
- Author:
Li WANG
1
;
Xiaoqiang SUN
1
;
Chengzhi LU
1
Author Information
1. Department of Cardiology, Tianjin First Central Hospital, Tianjin 300192, China.
- Publication Type:Monographicreport:Applicationofrenaldenervationinthetreatmentofhypertension
- Keywords:
hypertension;
renal nerve;
renal denervation;
renal nerve stimulation;
mapping/selective renal denervation
- From:
Chinese Journal of Clinical Medicine
2025;32(6):949-952
- CountryChina
- Language:Chinese
-
Abstract:
Renal denervation (RDN) as an interventional approach for treating refractory hypertension has developed a variety of ablation strategies and different energy ablation techniques. This article reviews the principles, characteristics, clinical advantages, and the latest research progress of mapping/selective RDN system. Selective RDN identifies “hot spots” (sympathetic nerve-rich points) through renal nerve stimulation (RNS) for targeted ablation, while avoiding “cold spots” (parasympathetic nerve-rich points) and “neutral points”, achieving more precise sympathetic nerve regulation. Animal experiments and clinical studies have shown that mapping/selective RDN can more effectively lower blood pressure, achieve blood pressure targets, and reduce the burden of antihypertensive drugs (reducing the drug index by 3.25). Mapping/selective RDN system provides a personalized solution for hypertension treatment, improving treatment efficiency and reducing complications.
