Psoriasis vulgaris and vitiligo are chronic autoimmune skin conditions that affect all races and age groups. Psoriasis presents as erythematous plaques with silvery scales, while vitiligo manifests as symmetric depigmented macules. Their co-occurrence, although documented since 1955, remains relatively rare and underreported in Asian populations. We report the case of a 54-year-old Filipino male, with no known comorbidities who presented with both psoriasis and vitiligo. Skin punch biopsies confirmed the diagnoses of both conditions. During treatment, new vitiliginous lesions appeared over psoriatic plaques, suggesting Koebnerization. We review the current literature to explore possible immunologic and genetic overlaps and provide insights to their treatment.