Epidemiological characteristics of brucellosis in humans in Zhangjiakou City， Hebei Province from 2018 to 2023
10.19428/j.cnki.sjpm.2025.24564
- VernacularTitle:2018—2023年河北省张家口市人间布鲁菌病流行特征
- Author:
Fei SUN
1
;
Yong MA
2
;
Xiaoli HAN
3
;
Xiong ZHANG
4
;
Huisheng ZHAO
5
;
Dong YAN
6
Author Information
1. Zhangjiakou Center for Disease Control and Prevention, Zhangjiakou, Hebei 075000, China
2. Zhangjiakou Institute of Endemic Diseases Control and Prevention, Zhangjiakou, Hebei 075000,China
3. Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, Hebei 050000 ,China
4. Guyuan County Center for Disease Control and Prevention, Zhangjiakou, Hebei 076500, China
5. Chicheng County Center for Disease Control and Prevention, Zhangjiakou, Hebei 075500, China
6. Anti-plague Institute of Hebei Province, Zhangjiakou, Hebei 075000, China
- Publication Type:Journal Article
- Keywords:
brucellosis in humans;
epidemiology;
spatial clustering;
Joinpoint regression
- From:
Shanghai Journal of Preventive Medicine
2025;37(10):830-834
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the epidemiological characteristics and spatial clustering patterns of brucellosis in humans in Zhangjiakou City, Heibei Province from 2018 to 2023, so as to provide a basis for the prevention and control of brucellosis. MethodsIncidence data of brucellosis in Zhangjiakou City from 2018 to 2023 were collected. Descriptive epidemiological analysis, Joinpoint regression modelling, and spatial autocorrelation analysis were used to analyze the temporal trends and spatial clustering patterns of the epidemic. ResultsA total of 3 812 cases of brucellosis were reported in Zhangjiakou City from 2018 to 2023, with no death case, yielding an average annual incidence rate of 15.43/100 000 (incidence range: 12.82/100 000‒17.76/100 000). Cases of brucellosis occurred year-round, with a distinct seasonal pattern, predominantly concentrated between March and September, peaking in May and June. The male-to-female ratio was 2.58∶1, with a higher incidence in males than that in females. The highest incidence rates were observed in the 40‒<50 years (74.98/100 000) and 50‒<60 years age group (87.14/100 000). The majority of cases were farmers and herdsmen (3 557 cases, 93.31%). Joinpoint regression analyses indicated that from 2018 to 2023, the incidence rate of human brucellosis in pastoral areas of Zhangjiakou City showed a declining trend (APC=-9.70%, 95%CI: -15.31%‒ -4.63%), while the incidence rate in mixed-use areas exhibited an increasing trend (APC=6.90%, 95%CI: 0.17%‒14.30%). Spatial clustering analyses showed that the incidence of brucellosis in Zhangjiakou from 2018 to 2023 was non-randomly distributed across the whole city, with a positive spatial correlation and significant clustering (Moran’s I>0, all P<0.001). Local spatial autocorrelation analyses showed that the high-high clusters were concentrated in the pastoral areas during 2018‒2020. From 2021 onward, the number of high-high clusters in mixed and non-pastoral regions exceeded those in traditional pastoral areas. ConclusionFrom 2018 to 2023, the incidence of brucellosis in Zhangjiakou City showed a declining trend, with significant spatial clustering observed across the city. It is recommended to intensify health education among males aged 40‒<60 years. Scientific livestock management practices should be promoted in non-pastoral and mixed areas, and cross-sectoral quarantine and joint prevention and control efforts should be strengthened as well.
