Platelet-rich plasma in the treatment of interstitial cystitis/bladder pain syndrome:a single-center prospective study
10.3969/j.issn.1009-8291.2025.12.005
- VernacularTitle:富血小板血浆治疗间质性膀胱炎/膀胱疼痛综合征的临床疗效观察：一项单中心前瞻性研究
- Author:
Jin HUANG
1
;
Rong LYU
1
;
Wenjun MENG
1
;
Tingting LYU
1
;
Weilin FANG
1
;
Jianwei LYU
1
Author Information
1. Department of Urology, Gongli Hospital, Pudong New District, Shanghai 200135, China
- Publication Type:Journal Article
- Keywords:
interstitial cystitis/bladder pain syndrome;
platelet-rich plasma;
bladder capacity
- From:
Journal of Modern Urology
2025;30(12):1043-1048
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of platelet-rich plasma (PRP) therapy for interstitial cystitis/bladder pain syndrome (IC/BPS). Methods This single-center prospective study involved 97 IC/BPS patients treated in our hospital during Sep.2023 and Apr.2025, who underwent transurethral bladder injection of PRP. The injections were administered once a month for four sessions. The global response assessment (GRA) score,24-hour urinary frequency, maximum single voiding volume, visual analogue scale (VAS) score, O'Leary score, pelvic pain, urgency and frequency (PUF) score, and Zung self-rating anxiety scale (SAS) score were analyzed. Results All 97 patients completed four injections. The GRA score,24-hour urinary frequency, VAS score, O'Leary score and PUF score were improved significantly after treatment (P<0.007). Intraoperative bladder capacity with significant improvement were observed after the first injection (P<0.01), and the maximum urine output were observed after the fourth injection (P<0.007). The SAS score was not significantly improved. Conclusion Repeated PRP injections can effectively alleviate bladder pain, improve frequent and urgent urination symptoms, and increase the bladder capacity.
