Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer
10.3971/j.issn.1000-8578.2025.25.0438
- VernacularTitle:KRAS G12C突变晚期非小细胞肺癌治疗研究进展
- Author:
Yi LIU
1
;
Zhen HUANG
1
;
Lulu CHEN
1
;
Qibin SONG
1
Author Information
1. Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, China.
- Publication Type:REVIEWS
- Keywords:
KRAS G12C;
Non-small cell lung cancer;
Targeted therapy
- From:
Cancer Research on Prevention and Treatment
2025;52(12):1012-1020
- CountryChina
- Language:Chinese
-
Abstract:
This article elucidates therapeutic approaches for KRAS G12C-mutant advanced non-small cell lung cancer, with focus on global advancements in inhibitor research. It also summarizes clinical evidence on the efficacy of targeted agents in monotherapy and combination therapies, analyzes their clinical advantages and challenges, and explores future directions for novel treatment modalities.
