Advancements in Cell Membrane–Based Biomimetic Carriers for Antitumor Therapy
10.3971/j.issn.1000-8578.2025.25.0550
- VernacularTitle:细胞膜仿生载体用于抗肿瘤治疗的研究进展
- Author:
Jiahe WU
1
;
Nan WANG
2
;
Jianqing GAO
3
;
Nengming LIN
1
Author Information
1. Department of Clinical Pharmacy, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China.
2. Department of Clinical Pharmacy, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China;State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
3. State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
- Publication Type:SPECIALFEATURE
- Keywords:
Cell membrane-based biomimetic carrier;
Drug delivery;
Antitumor therapy
- From:
Cancer Research on Prevention and Treatment
2025;52(12):973-979
- CountryChina
- Language:Chinese
-
Abstract:
Drug delivery technologies are crucial components in drug development, greatly enhancing drug bioavailability and therapeutic efficacy and reducing toxic side effects. Cell membrane-based biomimetic carriers have attracted considerable interest owing to their intrinsic biointeractive capability derived from source cells in vivo. This review summarizes the fundamental properties and functional attributes of cell membrane–based biomimetic carriers from different cellular sources and discusses their advancements in tumor-targeted drug delivery and role in the activation of antitumor immunity. Ultimately, the discussion focuses on the prospects and potential challenges in employing cell membrane-based biomimetic carriers for antitumor treatment.
