Effects of Thoracoscopic Surgery Versus Thoracotomy in Patients with Pathological Stage ⅡB-ⅢA Non-small Cell Lung Cancer by Propensity Score Matching Analysis
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0516
- VernacularTitle:基于倾向性评分的病理分期ⅡB~ⅢA期非小细胞肺癌患者胸腔镜与开胸手术的疗效比较
- Author:
Tian-ci ZHANG
1
;
Gao-xiang WANG
1
;
Guang-wen XU
1
;
Xin-hao LI
2
;
Ming-ran XIE
1
Author Information
1. Department of Thoracic Surgery， The First Affiliated Hospital of USTC， Hefei 230000， China
2. School of Basic Medical Sciences， Hebei North University， Zhangjiakou 075000， China
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
video-assisted thoracscopic surgery;
propensity score matching analysis
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2021;42(5):771-777
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo compare the short-term and long-term effects of video-assisted thoracoscopic surgery （VATS） versus thoracotomy in patients with Pathological stage ⅡB-ⅢA non-small cell lung cancer （NSCLC） and to explore the efficacy and safety of VATS. MethodsA total of 221 patients with VSCLC undergoing radical resection of lung cancer in Anhui Provincial Hospital from January 2010 to December 2016 were retrospectively analyzed and assigned to VATS and thoracotomy groups. Propensity score matching analysis were performed to compare the short-term and long-term effects. ResultsCompared with the thoracotomy group， the VATS group had the advantages of shorter postoperative hospitalization time， less intraoperative bleeding and less thoracic drainage （P <0.05）. Survival analysis showed the five-year survival in the VATS group was better than that of the thoracotomy group （P <0.05）. We also found the prognosis of VATS in the ⅢA stage group and adenocarcinoma group was better than that of the thoracotomy （P <0.05）. ConclusionsFor patients with stage IIB-ⅢA NSCLCs， VATS could not only reduce intraoperative bleeding ， postoperative thoracic drainage， shorten the length of the chest tube and hospitalization time， but also achieve node dissection similar to thoracotomy and prolong the survival time.
