Clinical Study on Pupil Diameter Under Dark Adaptation of SMILE
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0514
- VernacularTitle:SMILE术暗适应下瞳孔直径的影响因素分析
- Author:
Hai-qin LIN
1
;
Quan LIU
1
Author Information
1. State Key Laboratory of Ophthalmology， Zhongshan Ophthalmic Center， Sun Yat-sen University， Guangzhou 510060， China
- Publication Type:Journal Article
- Keywords:
pupil diameter under dark adaptation;
factors related with pupil;
eye type;
dominant eye;
preoperative equivalent spherical degree
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2021;42(5):756-761
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo compare the consistency between handheld pupil measuring instrument and Sirius anterior segment analysis system in measuring pupil diameter under dark adaptation， and explore the changes of pupil diameter under dark adaptation after small incision lenticule extraction （SMILE） surgery and the factors affecting pupil diameter under dark adaptation. MethodsThis study is divided into two parts. ① One hundred and twenty-eight patients （256 eyes） who underwent SMILE surgery were included in this study. Besides， the pupil diameter under dark adaptation of the same eye， before and 3 months after surgery， were measured by two methods. The data were analyzed by Wilcoxon matched-pairs signed rank sum test and simple linear regression analysis. ② A retrospective study included 2 237 patients （4 179 eyes in total） who underwent SMILE surgery， and data of pupil diameter under dark adaptation， age， gender， eye type， dominant eye and equivalent spherical power were collected for analysis. ResultsThere was no significant difference between the pupil diameter under dark adaptation measured by hand-held pupil measuring instrument （ŷ
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） and that measured by Sirius anterior segment analysis system （P=0.369）. Simple linear regression analysis was performed （ŷ![]()
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=0.929x+0.453， r²=0.858）. The difference of pupil diameter under dark adaptation before SMILE surgery （x， 6.80±0.88） mm and pupil diameter under dark adaptation 3 months after SMILE surgery （ŷ![]()
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， 6.65±0.73） mm was statistically significant （P=0.018）. Simple linear regression analysis showed that ŷ![]()
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=1.050x-0.223 and r²=0.771. This is an epidemiological study on influencing factors of pupil diameter under dark adaptation. ① Correlation analysis between pupil diameter under dark adaptation and age showed that there was a negative correlation between them （r=-0.204， P=0.000）. ② The pupil diameter under dark adaptation of male group （6.35±0.75） mm was significantly different from that of female group （6.27±0.74） mm （P=0.000）. ③ There was no significant difference between the right eye group （6.29±0.74） mm and the left eye group （6.31±0.75） mm. ④ There was no significant difference between the dominant eye group （6.30±0.73） mm and the non-dominant eye group （6.31±0.75） mm. ⑤ There is no statistically significant difference among low myopia group （6.23±0.73） mm， moderate myopia group （6.31±0.74） mm， high myopia group （6.30±0.75） mm and super high myopia group （6.33±0.70） mm. Conclusions① Hand-held pupil measuring instrument and Sirius anterior segment analysis system are consistent in measuring pupil diameter under dark adaptation before surgery. Therefore， in refractive surgery， hand-held pupil measuring instrument can be used to measure pupil diameter under dark adaptation instead of Sirius anterior segment analysis system. ② The pupil diameter under dark adaptation 3 months after SMILE surgery tends to decrease， compared with that before SMILE surgery. ③ Pupil diameter under preoperative dark adaptation is negatively correlated with age. Pupil diameter under preoperative dark adaptation is larger in men than that in women. Pupil diameter under preoperative dark adaptation has nothing to do with eye type， dominant eye and preoperative equivalent spherical degree.
