Syndrome Differentiation and Treatment of Alopecia Areata Based on the Turbid Toxin Theory from the Perspectives of the Liver，Spleen，and Kidney
10.13288/j.11-2166/r.2025.23.016
- VernacularTitle:基于浊毒理论从肝、脾、肾辨治斑秃
- Author:
Jiaqi LI
1
;
Wenzhao HAN
1
;
Qian YANG
2
;
Yuhang LIU
3
;
Yuxin ZHANG
1
;
Nan JIANG
1
;
Weiye LI
3
;
Xiang LIU
3
Author Information
1. Graduate School，Hebei University of Chinese Medicine，Shijiazhuang，050091
2. Hebei Provincial Hospital of Traditional Chinese Medicine
3. The First Affiliated Hospital of Hebei University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
alopecia areata;
turbid toxin;
liver;
spleen;
kidney;
qi movement disorder
- From:
Journal of Traditional Chinese Medicine
2025;66(23):2494-2498
- CountryChina
- Language:Chinese
-
Abstract:
Alopecia areata （AA） is a common hair loss disorder， and the core pathogenesis is the internal gene-ration of turbid toxin caused by qi movement disorder in the liver， spleen， and kidney. Turbid toxin serves as both a pivotal etiological trigger and a pathological driver of disease exacerbation. Clinically， AA can be classified into four principal patterns， including liver constraint with spleen deficiency， internal accumulation of damp-heat， liver-kidney depletion， and qi-blood depletion. Therapeutic strategies prioritize clearing and resolving turbid toxin while regulating the qi movement of the liver， spleen， and kidney. Accordingly， different formulas were applied. Self-formulated Shugan Jianpi Huazhuo Formula （疏肝健脾化浊方） is suggested to drain dampness， resolve turbidity， and unblock qi movement. Self-formulated Sanjiao Fenxiao Jiedu Formula （三焦分消解毒方） can be used to clear heat， drain dampness and resolve toxin. Self-formulated Zishen Yanggan Toudu Decoction （滋肾养肝透毒汤） can clear and vent latent toxins， while Self-formulated Guiqi Shengfa Didu Formula （归芪生发涤毒方） is employed to tonify qi and blood， purge toxins， and regenerate vitality. By differentiating and treating AA based on the functional patterns of the liver， spleen， and kidney， this approach expands the application scope of the turbid toxin theory and provides valuable insights for treatment of AA.
