Pathogenesis and Therapeutic Approaches of Systemic Lupus Erythematosus Secondary Gynecological and Obstetric Diseases Based on the Theory of "Bi （痹） of both Body and Viscera"
10.13288/j.11-2166/r.2025.23.008
- VernacularTitle:“体脏合痹”理论视角下系统性红斑狼疮继发妇产科疾病的病机及诊疗思路
- Author:
Hui XU
1
;
Quan JIANG
1
;
Congmin XIA
1
;
Rouman ZHANG
1
;
Xun GONG
1
;
Chuanhui YAO
1
;
Zixia LIU
1
;
Yuchen YANG
1
;
Xieli MA
1
Author Information
1. Guang'anmen Hospital， China Academy of Chinese Medical Sciences，Beijing，100053
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
bi （痹） of both body and viscera;
ovarian reserve function;
menstrual disorders;
pregnancy outcomes
- From:
Journal of Traditional Chinese Medicine
2025;66(23):2438-2442
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus （SLE） may lead to secondary gynecological and obstetric disorders such as decreased ovarian reserve function， menstrual abnormalities， and adverse pregnancy outcomes. Based on "bi （痹） of both body and viscera" theory， this paper proposed that the core mechanism of SLE secondary gynecological and obstetric diseases lies in the mutual transformation between "body bi" and "viscera bi"， which together affect the uterus. Physiologically， uterus forms an internal-external network with the body and viscera through the meridians and blood vessels. Pathologically， when the healthy qi is deficient， nourishment of the body and viscera is impaired； when toxins and stasis accumulate， pathogenic factors disturb the uterus through the chong （冲） and ren （任） meri-dians. The resulting obstruction in the uterus can， in turn， manifest externally and aggravate damage to the body and viscera. Therefore， the pathogenesis of SLE secondary gynecological and obstetric diseases follows a dynamic trajectory of "body bi first， body bi affecting viscera， and then bi of both body and viscera". In treatment， the principle of harmonizing and balancing the healthy qi is emphasized. The main approach is to regulate the viscera， stabilize the body， and nourish the uterus， with the coordination of nourishing the viscera through the body， thereby achieving simultaneous treatment of both body and viscera. This highlights the guiding significance of the "bi of both body and viscera" theory in preventing and treating SLE secondary gynecological and obstetric diseases.
