Research progress on the role and mechanism of Traditional Chinese Medicine in preventing and treating influenza virus pneumonia
10.12206/j.issn.2097-2024.202402033
- VernacularTitle:中药防治流感病毒性肺炎的作用及机制研究进展
- Author:
Binguo LIU
1
;
Baoting WU
1
;
Jianli WANG
1
;
Zhuqing CHEN
1
Author Information
1. No.983 Hospital of Joint Logistic Support Force, Tianjin 300142, China.
- Publication Type:Reviews
- Keywords:
Traditional Chinese Medicine;
influenza virus-induced pneumonia;
active ingredients;
drug development
- From:
Journal of Pharmaceutical Practice and Service
2025;43(11):540-547
- CountryChina
- Language:Chinese
-
Abstract:
Influenza virus pneumonia （IVP） is an acute inflammatory disease of the lung with high incidence rate and infectivity caused by invading of the virus into the lower respiratory tract. At present, the treatment of IVP is mainly based on anti-influenza virus infection strategies, including the use of influenza vaccines and anti-influenza virus drugs. Due to the strong variability of viral antigens, it is difficult to obtain long-lasting immunity through vaccination. Commonly used chemical//biological antiviral drugs usually target a single specific viral protein. The mutation and evolution of the virus can reduce its efficacy or render it ineffective, which may lead to drug resistance, limiting the clinical application of these treatment options. Traditional Chinese Medicines （TCMs） have a long history in the prevention and treatment of IVP and are widely used in clinical practice due to their unique advantages and clear therapeutic effects. The research progress on the pathogenesis of IVP, effective prevention and treatment of TCMs for IVP, and the mechanism of action of its active ingredients were reviewed, which could provide new ideas for the treatment of IVP and reference for the development of new multi-target and low toxicity drugs.
