Study of the factors associated with colorectal cancer
- VernacularTitle:Бүдүүн, шулуун гэдэсний хавдарт нөлөөлөх хүчин зүйлийн судалгаа
- Author:
Ankhzaya B
1
;
Enkhmend Kh
1
;
Nomin-Erdene D
1
;
Bolor U
1
;
Nyamsuren M
2
;
Sonor Z
3
;
Chinzorig M
4
;
Erkhembayar E
4
;
Tsenguun G
1
;
Yumchinsuren Ts
1
;
Ganchimeg D
1
;
Tegshjargal B
1
;
Tulgaa L
1
;
Batbold B
1
Author Information
1. Institute of Medical Sciences
2. State Third Clinical Hospital
3. State Second Clinical Hospital
4. Institute of Medical Sciences;National Cancer Center
- Publication Type:Journal Article
- Keywords:
colorectal cancer;
risk factor;
food consumption
- From:Mongolian Medical Sciences
2025;211(1):18-27
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:According to the World Health Organization (WHO) data from 2022, 19.9 million people were
diagnosed with cancer globally, and 9.7 million people died from the disease. In recent years,
the incidence of colorectal cancer (CRC) has been rapidly increasing, ranking 4th among all
cancers with 18.4 cases and 8.1 deaths per 100,000 population. In Mongolia, 826 new cases
of CRC have been registered over the past six years, with an incidence rate of 8.2 cases and
a mortality rate of 5.03 per 100,000 population. It is projected that by 2030, the incidence will
reach 13.28 cases and the mortality rate will rise to 8.72 per 100,000 population. We aimed
to comprehensively examine the risk factors for colorectal cancer among the population
of Mongolia, establish a scientific basis for early detection and prevention, and strengthen
preventive measures.
Materials and Methods:A case-control study was conducted from 2022 to 2024. The study enrolled a total of 305
subjects, including 98 patients with colorectal cancer, 101 patients with colon polyps, and
106 healthy subjects. The risk. questionnaire consisted of 50 questions divided into 10
sections. All statistical analysis was performed with SPSS version 23.0 software (SPSS Inc.,
Chicago, IL, USA) and P value <0.05 was considered statistically significant. categorical
data was represented as numbers and percentages. Pearson’s chi-squared and Fisher’s
exact test were used to compare categorical variables. Multivariate logistic regression was
used to identify the risk factor associated with recurrence. The study protocol was approved
by Ethics Review Committee of Ministry of Health of Mongolia on 17 March 2023 (approval
number: 23/012).
Results:The average age of the participants was 57.1±12.8 years. Among all study participants,
37.6% (115) were male and 62.4% (188) were female. Comparison of colorectal cancer
incidence by age and gender revealed no statistically significant differences (p=0.021;
p=0.422). Regular physical exercise was found to have a protective effect against colorectal
cancer (p=0.076; OR 0.341 95% Cl 0.118-.0986). The frequency of fruit consumption, 4 to 6
times per week (p=0.008, OR 0.08, 95% Cl 0.01-0.45), frequency of vegetable consumption
4 to 6 times per week (p<0.00; OR 0.07, 95% Cl 0.02-0.19), no dining out (0.007, OR 0.3,
95% Cl 0.18-0.68), and meat consumption (p=0.001) are decreased risk of colorectal cancer.
Conclusion:The patient's age and the presence of colon polyps are risk factors for colorectal cancer,
while regular physical activity and a diet rich in fruits and vegetables are protective factors
that help reduce the risk of developing colorectal cancer.
- Full text:2025122317161924747MAUS-2025-211(1)-18-27.pdf
