Research progress on hepatitis E virus infection and risk of transfusion transmission
10.13303/j.cjbt.issn.1004-549x.2025.10.022
- VernacularTitle:戊型肝炎病毒感染与输血传播风险研究进展
- Author:
Rui WANG
1
;
Bo WANG
2
;
Yang YU
1
Author Information
1. Department of Transfusion Medicine, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
2. The Southern Medical Branch of PLA General Hospital, Beijing 100071, China
- Publication Type:Journal Article
- Keywords:
hepatitis E virus(HEV);
infection;
transfusion transmission;
blood screening strategy
- From:
Chinese Journal of Blood Transfusion
2025;38(10):1444-1449
- CountryChina
- Language:Chinese
-
Abstract:
With the continuous increase in serum positivity rates for hepatitis E virus(HEV) worldwide, the number of reported cases of transfusion transmitted HEV among blood donors continues to rise. Moreover, transfusion transmitted HEV can lead to severe clinical outcomes in certain transfusion recipients. For instance, immunocompromised patients are at significantly higher risk of progressing to chronic infection, which may lead to serious consequences such as cirrhosis and liver failure, accompanied by an overall increase in mortality. HEV screening has emerged as an critical public health priority for both developing and developed countries. This article elaborates on the prevalence, transmission risk, and screening strategies of HEV infection, aiming to optimize blood donor screening strategies and ensure blood transfusion safety.
