A blood supply model for the emergency care of severe trauma
10.13303/j.cjbt.issn.1004-549x.2025.10.005
- VernacularTitle:严重创伤紧急救治阶段血液保障模式探讨
- Author:
Songlin HU
1
;
Zhiyuan WEI
2
;
Gaoxiang HUANG
2
;
Lijuan LIU
3
;
Mingwei FU
3
;
Junke TAN
3
;
Haozhe LI
3
;
Songtao LI
2
Author Information
1. Center of Trauma, No. 924 Hospital of PLA Joint Logistic Support Force, Guilin 541002, China; Department of Transfusion Medicine, No. 924 Hospital of PLA Joint Logistic Support Force, Guilin 541002, China; Guilin Blood Center of PLA, Guilin 541002, China
2. Center of Trauma, No. 924 Hospital of PLA Joint Logistic Support Force, Guilin 541002, China
3. Department of Transfusion Medicine, No. 924 Hospital of PLA Joint Logistic Support Force, Guilin 541002, China; Guilin Blood Center of PLA, Guilin 541002, China
- Publication Type:Journal Article
- Keywords:
whole blood transfusion;
traumatic shock;
refrigerated whole blood
- From:
Chinese Journal of Blood Transfusion
2025;38(10):1327-1333
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish and validate a whole blood (WB) supply model, thereby providing practical experience for the clinical application of WB in domestic trauma emergency care and informing the development of a wartime blood supply system for the military. Methods: A “10×24” WB supply model was established by formulating blood collection protocols, storage standards, and transfusion criteria. Multiple WB samples were tested under specific storage conditions to assess key indicators at different time points, including red blood cell (RBC), white blood cell (WBC), and platelet counts, hemoglobin concentration, coagulation parameters (PT, APTT, TT, FIB), coagulation factor activity, thromboelastography (TEG) parameters, and electrolyte levels. Additionally, clinical data from hemorrhagic patients who met the criteria for WB transfusion and were admitted between March and July 2024 were analyzed to evaluate WB transfusion volume. Results: RBC counts and hemoglobin levels remained stable in WB stored at 4℃ for up to 10 days. However, platelet counts and coagulation function (PT, APTT) significantly declined with prolonged storage, while potassium levels increased. From March to July 2024, the model was successfully applied to 23 patients with acute hemorrhage, with a median WB transfusion volume of 543 mL. A detailed case study of a severe traumatic hemorrhagic shock patient was reported, who was successfully treated with 5.5 units of refrigerated WB combined with component blood. Conclusion: The “10×24” WB supply model demonstrated acceptable changes in critical quality parameters under strict management and a 10-day rotation cycle. This model effectively supports the treatment of acute hemorrhage and holds promise for integration into the future wartime blood supply system of the military.
