Research progress of platelet function in immune regulation: from basic to clinical
- VernacularTitle:血小板在免疫调节中的功能研究进展：从基础到临床
- Author:
Weihua HUANG
1
;
Qiu SHEN
1
;
Heshan TANG
1
;
Ziyang FENG
1
;
Min YE
1
;
He ZHANG
1
;
Ying LIU
1
;
Baohua QIAN
1
;
Zhanshan CHA
1
Author Information
- Publication Type:Journal Article
- Keywords: platelets; immune regulation; function; basic; clinical
- From: Chinese Journal of Blood Transfusion 2025;38(11):1592-1601
- CountryChina
- Language:Chinese
- Abstract: Traditionally, platelets, which are anucleate cell fragments derived from blood cells, have been primarily associated with their pivotal functions in hemostasis and thrombosis. However, recent research has elucidated their significant role in immune regulation, highlighting their expression of various immune receptors, involvement in numerous immune-related signaling pathways, and activation of diverse effector functions. This paper elaborates on the fundamental biological characteristics and immune functions of platelets, the involvement of activated platelets in immune regulation, and their prospective applications in clinical therapy. Furthermore, the paper discusses future directions in platelet immune research, as well as the prospects and developmental trends in immunotherapy, aiming to furnish a thorough reference for the investigation and clinical utilization of platelets within the domain of immune regulation.
