A convergent mixed-methods study on the maternal influenza vaccination willingness among pregnant and postpartum women in Shanghai and Liaoning Province
10.19428/j.cnki.sjpm.2025.250112
- VernacularTitle:基于聚敛式混合方法研究上海和辽宁地区孕产妇妊娠期流感疫苗的接种意愿
- Author:
Fanyu ZENG
1
;
Honghong YANG
2
;
Hong JIANG
1
;
Chunyi GU
3
;
Fengyun YANG
4
;
Longmei JIN
5
;
Changhui LI
2
;
Haiqi WANG
4
;
Xu QIAN
1
Author Information
1. School of Public Health, Fudan University, NHC Key Laboratory of Health Technology Assessment, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai 200032, China
2. Liaoning Maternal and Child Health Hospital, Shenyang, Liaoning 110000, China
3. Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China
4. Shanghai Jiading Maternal and Child Health Care Hospital, Shanghai 201800, China
5. Shanghai Minhang Maternal and Child Health Care Hospital, Shanghai 201102, China
- Publication Type:Journal Article
- Keywords:
influenza;
vaccination;
pregnancy period;
cross-sectional study
- From:
Shanghai Journal of Preventive Medicine
2025;37(9):781-787
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the current status and related factors of maternal influenza vaccination willingness among pregnant and postpartum women in Shanghai and Liaoning Province, China, and to explore the facilitators and barriers affecting vaccination uptake, so as to provide references for future practices in promoting maternal influenza immunization in China. MethodsA convergent mixed-methods research was conducted. From January to March 2024, a questionnaire survey was conducted among women attending prenatal and postnatal care at 7 medical institutions in Shanghai and Dalian, Liaoning Province, which aimed to assess pregnant women’s knowledge about influenza vaccine and their willingness to vaccination during pregnancy, as well as to identify the related factors. In addition, purposive sampling method was used to conduct in-depth interviews with pregnant women and perinatal healthcare service providers to explore their perspectives on influenza vaccination during pregnancy, including the reasons for their willingness or unwillingness to receive ( or recommend) the vaccine, and the relevant facilitators and barriers to vaccination. ResultsA total of 366 pregnant and postpartum women participated in the questionnaire survey, and 9.56% (35/366) of them were willing to receive the influenza vaccine during pregnancy. The results of multivariate logistic stepwise regression analyses showed that primipara (aOR=0.158, 95%CI: 0.037‒0.671, P=0.012), family members’ support for influenza vaccination during pregnancy (aOR=0.015, 95%CI: 0.003‒0.082, P<0.001) were associated with higher willingness to receive influenza vaccine during pregnancy. Absence of influenza infection during pregnancy (aOR=5.383, 95%CI: 1.801‒16.092, P<0.001), and lack of knowledge regarding influenza vaccination during pregnancy (aOR=11.294, 95%CI: 3.593‒35.496, P<0.01) were associated with lower willingness to receive influenza vaccine during pregnancy. Qualitative findings indicated that the facilitators to vaccination willingness among pregnant and postpartum women included the recommendation of healthcare service providers, adequate knowledge of influenza vaccine information and family members’ support for vaccination. Conversely, the barriers to vaccination willingness included low recommendation from the healthcare service providers, lack of knowledge about the safety of influenza vaccine during pregnancy and inadequate attention to influenza and influenza vaccine. ConclusionThe willingness to receive influenza vaccination among pregnant and postpartum women in Shanghai and Liaoning Province is relatively low. It is recommended that China should promptly improve the evidence-based system for the safety and efficacy of influenza vaccines for pregnant and postpartum women, along with an establishment of the mechanism for addressing adverse reactions. Furthermore, it is essential to enhance educational outreach to pregnant and postpartum women, their families, and healthcare service providers, thereby increasing the accessibility of information regarding influenza vaccination, which are expected to enhance the willingness of pregnant and postpartum women to receive the vaccine.
