Relative Tumor Density of Soft-Tissue Sarcoma in Korean Population:An Institutional Review
- Author:
Bo Bin CHA
1
;
Jung Yup KIM
;
Won-Serk KIM
;
Ga-Young LEE
;
Young-Jun CHOI
Author Information
- Publication Type:Original Article
- From:Annals of Dermatology 2025;37(2):96-104
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:Comprehensive studies on the tumor burden of soft-tissue sarcoma (STS) by anatomical site are lacking in Asian populations.
Objective:To investigate the anatomical distribution of STS via relative tumor density (RTD) in a Korean cohort.
Methods:The RTDs of patients with STS at a single-institution from 2007–2022 were retrospectively analyzed. To describe the STS locations, the body was divided into 4 anatomical sites, and the RTD of each was calculated to the compare topographic tumor burden.
Results:Fifty-nine cases in 58 individuals, 35 male (60.3%) and 23 female (39.7%), with a mean age of 56.5±20.4 were analyzed. Overall, the most frequent STS site was the lower extremity (LE, n=22, 37.3%), and the highest RTD was in the head and neck (H&N, 2.44; 95% confidence interval, 1.39–3.77). Dermatofibrosarcoma protuberans (DFSP), Kaposi’s sarcoma (KS), and angiosarcoma (AS) accounted for 76.3% of all the cases. DFSP, KS, and AS showed significantly higher RTD on the trunk (2.55, p=0.025), LE (3.88, p<0.001), and H&N (7.42, p<0.001), respectively, than elsewhere.
Conclusion:Each STS displays topographic variability and produces different topographic tumor burdens by body site in an Asian population.
