Application of peripheral blood inflammatory markers in prognosis evaluation of patients with acute-on-chronic liver failure
- VernacularTitle:外周血炎症指标在慢加急性肝衰竭患者预后评估中的应用
- Author:
Xuefang YANG
1
;
Xiaoqing YANG
1
;
Haiwen MA
1
;
Wenjuan SHI
1
;
Hong WAN
1
;
Jianyun WANG
1
Author Information
- Publication Type:Review
- Keywords: Acute-on-Chronic Liver Failure; Inflammation; Prognosis
- From: Journal of Clinical Hepatology 2025;41(11):2418-2423
- CountryChina
- Language:Chinese
- Abstract: Acute-on-chronic liver failure （ACLF） refers to severe liver dysfunction that occurs on the basis of chronic liver diseases， and it is characterized by rapid disease progression， poor prognosis， and high mortality rate. In recent years， inflammatory markers have become a research hotspot due to their significant role in assessing the prognosis of ACLF. This article reviews the advances in the application of inflammatory markers in assessing the prognosis of ACLF， such as systemic immune inflammatory index， lymphocyte-white blood cell ratio， neutrophil-lymphocyte ratio， and C-reactive protein， and discusses their clinical value and future research directions， in order to provide a theoretical basis for the early intervention and prognosis management of ACLF patients.
