Progress in research on group B Neisseria meningitidis vaccine
10.13200/j.cnki.cjb.004613
- VernacularTitle:B群脑膜炎球菌疫苗的研究进展
- Author:
Tiejun GU
1
Author Information
1. School of Life Science, Jilin University, Changchun 130012, Jilin Province, China
- Publication Type:Journal Article
- From:
Chinese Journal of Biologicals
2025;38(12):1510-1515
- CountryChina
- Language:Chinese
-
Abstract:
B Neisseria meningitidis,MenB）逐步成为导致全球侵袭性脑膜炎的主要病原体之一。本文对国外已上市MenB疫苗和新的潜在抗原的发现作一综述，为疫苗研制提供参考。
Neisseria meningitidis(Nm) is the primary pathogen causing epidemic cerebrospinal meningitis, which can be classified into 13 serogroups based on its capsular polysaccharides. With the successful development and widespread use of meningococcal vaccines targeting serogroups A, C, Y, and W135, group B Neisseria meningitidis(MenB) has gradually become one of the main pathogens responsible for invasive meningococcal disease(IMD). This paper reviews the commercially available MenB vaccines overseas and the recent discovery of potential MenB antigens, aiming to provide reference for MenB vaccine research and development.
