Association between edentulism and the risk of social isolation in middle-aged and older adults
10.12016/j.issn.2096-1456.202550238
- Author:
DUAN Chengwei
1
;
LUO Mingyi
2
;
FAN Chenrui
2
;
XU Jialei
2
;
MUHETAER Tureke
3
;
XU Mengyuan
1
;
WAN Weiping
1
;
LIAO Haiqing
2
;
WU Zeni
1
Author Information
1. School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College
2. Department of Periodontology and Oral Mucosal Diseases, School of Stomatology/Affiliated Stomatological Hospital, Guangxi Medical University
3. School of Public Health, Xinjiang Medical University
- Publication Type:Journal Article
- Keywords:
middle-aged and older adults;
edentulism;
social isolation;
China Health and Retirement Longitu⁃ dinal Study;
cohort study;
Cox regression;
effect modification;
follow-up
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2025;33(12):1070-1077
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between edentulism and the risk of social isolation in middle-aged and elderly populations, provide empirical evidence for formulating social isolation prevention and intervention policies targeting edentulous middle-aged and elderly populations.
Methods:Data were derived from the baseline survey (2011) and three follow-ups (2013, 2015, 2018) of the China Health and Retirement Longitudinal Study (CHARLS). Participants were enrolled in the follow-up from the baseline. Those identified as socially isolated in any of the follow-up surveys conducted in 2013, 2015, or 2018 were considered to have reached the endpoint; otherwise, the follow-up was continued until the end of the 2018 survey; 9 870 individuals were ultimately included. Subjects were grouped by edentulism status. Chi-square test and multivariate Cox regression analysis were performed using Stata 17.0.
Results:During a median follow-up of 6.54 years, 1 800 cases of social isolation occurred, with an incidence rate of 18.23%（17.47%~18.99%）. Multivariate Cox regression showed that edentulism was associated with an increased risk of social isolation (HR=1.21, 95% CI: 1.03-1.42) after adjusting for confounders. Subgroup analysis revealed population heterogeneity. Sensitivity analyses confirmed the stability of the results.
Conclusion:Edentulism is associated with an increased risk of social isolation in middle-aged and elderly adults.
- Full text:2025121815030784389中老年人群无牙颌与社会隔离发生风险的关联研究.pdf
