Progress in Animal and Clinical Studies on the Impact of Bisphosphonates on Implant Stability.
10.3881/j.issn.1000-503X.16365
- Author:
Ling-Lu JIA
1
;
Zi-Kai GONG
2
;
Wen-Xi ZHAO
2
;
Yong WEN
2
Author Information
1. Department of Prosthodontics,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University,Jinan 250012,China.
2. Shandong Key Laboratory of Oral Tissue Regeneration,Jinan 250012,China.
- Publication Type:Review
- Keywords:
bisphosphonates;
implants;
medication-related osteonecrosis of the jaw;
osseointegration
- MeSH:
Humans;
Dental Implants;
Animals;
Diphosphonates/pharmacology*;
Osseointegration/drug effects*;
Bisphosphonate-Associated Osteonecrosis of the Jaw
- From:
Acta Academiae Medicinae Sinicae
2025;47(4):628-633
- CountryChina
- Language:English
-
Abstract:
Bisphosphonates(BP),a class of commonly used medications for treating osteoporosis and bone malignancies,significantly affect bone metabolism.When dental implants are placed in patients receiving BP,the potential impacts of BP on the formation and long-term maintenance of implant osseointegration cannot be ignored.In addition,the influence of dental implants on the occurrence of BP-related osteonecrosis of the jaw is garnering attention.This article explores the influences of BP on the stability of dental implants based on a review of previous animal and clinical studies,discusses the impact of dental implants on the occurrence of BP-related osteonecrosis of the jaw,and proposes suggestions for the dental implant treatment of patients taking BP in clinical practice.This review is expected to provide a theoretical basis for the related research and clinical treatment.
