Value of 6-Minute Walking Test in Predicting Acute Mountain Sickness.
10.3881/j.issn.1000-503X.16373
- Author:
Yu-Fan JIANG
1
;
Qiang MA
2
;
Hai-Wei CHEN
2
;
Bao-Shi HAN
2
;
Bin FENG
2
;
Yun-Dai CHEN
1
Author Information
1. Department of Cardiology,The First Medical Center,Chinese PLA General Hospital,Beijing 100853,China.
2. Department of Cardiology,The Sixth Medical Center,Chinese PLA General Hospital,Beijing 100048,China.
- Publication Type:Journal Article
- Keywords:
6-minute walking test;
Lake Louise score;
acute mountain sickness
- MeSH:
Humans;
Altitude Sickness/diagnosis*;
Male;
Adult;
Female;
Young Adult;
Middle Aged;
Acute Disease;
Walk Test;
Walking;
Altitude;
Exercise Test
- From:
Acta Academiae Medicinae Sinicae
2025;47(4):535-541
- CountryChina
- Language:English
-
Abstract:
Objective To evaluate the value of pre-ascent 6-minute walking test performed at a high altitude in predicting the incidence of acute mountain sickness(AMS)induced by rapid ascent to a very high altitude.Methods After baseline information was collected,participants completed the 6-minute walking test at a high altitude of 2 900 m.Then,they rapidly ascended to a very high altitude of 5 000 m.The Lake Louise score was recorded to assess AMS.Results The AMS group showed a shorter pre-ascent 6-minute walking distance(6MWD)at the high altitude than the non-AMS group[480.00(450.00,521.75)m vs.546.00(516.50,568.50)m,P=0.006].No difference was observed regarding the pre-ascent heart rate or peripheral oxygen saturation(both P>0.05).The pre-ascent 6MWD at the high altitude was negatively correlated with the Lake Louise score assessed after rapid ascent to the very high altitude(r=-0.497,P=0.012).Logistic regression analysis confirmed that the pre-ascent 6MWD at the high altitude was associated with the risk of AMS induced by rapid ascent to the very high altitude(OR=0.971,95% CI=0.947-0.996,P=0.022).The results indicated that the pre-ascent 6MWD demonstrated ideal prediction performance(area under receiver operating characteristic curve=0.846,P=0.006).Conclusion The pre-ascent 6MWD recorded at the high altitude is a convenient and reliable predictor of the AMS induced by rapid ascent to the very high altitude.
