Advances in Influencing Mechanisms and Therapeutic Effects of Bacteriophages on Cancer.
10.3881/j.issn.1000-503X.16282
- Author:
Yu-Yang XIAO
1
;
Yu-Yang MA
1
;
Yi-Bo ZHANG
1
;
Cheng CHEN
1
;
Yang MENG
1
;
Ming-Yi ZHAO
1
Author Information
1. Department of Pediatrics,The Third Xiangya Hospital of Central South University,Changsha 410013,China.
- Publication Type:Journal Article
- Keywords:
bacteriophage;
bacteriophage therapy;
bacteriophage-bacterium interaction;
cancer
- MeSH:
Humans;
Bacteriophages;
Microbiota;
Neoplasms/therapy*;
Phage Therapy
- From:
Acta Academiae Medicinae Sinicae
2025;47(3):470-477
- CountryChina
- Language:English
-
Abstract:
Cancer brings about an enormous threat to human health,making the exploration of its mechanisms and therapeutic strategies a current focal point and challenge in research.Bacteriophages are integral components of the human microbiome,and studies have shown their influences on tumor growth and metastasis and their pivotal role in cancer treatment.This article elucidates the mechanisms by which bacteriophages impact the occurrence and development of cancer from their interactions with cancer cells,effects on bacteria,and influence on the immune system.Additionally,it explores bacteriophage-based strategies in cancer treatment and their potential in this field.This article aims to bring new thoughts and insights to the research in this field.
